Dr Fredrick Sawe is the Director of the Kenya Medical Research Institute/Walter Reed Project (KEMRI/WRP) Kericho site responsible for all research and HIV/AIDS related prevention, care, and treatment activities. Under the United States Military HIV Research Program (MHRP) Dr. Sawe has conducted several HIV/AIDS studies including HIV vaccine, therapeutics and cohort studies, double- blind, randomized controlled, IND/FDA regulated, from phase I to III, DAIDS and non-DAIDS sponsored studies.  Dr. Sawe has been/is a Co-chair, Principal Investigator (PI) and Associate Investigator of 2, 10 and 30 studies respectively that are either ongoing, about to start or closed to follow up. The HIV vaccine studies included four phase I/II multiclade, primed -boosted studies. Other relevant studies include COVID, MERS, Ebola, Polio, two age descending enteric shigella, yellow fever and others (typhoid, shigella, controlled human infection, COVID) vaccine studies in regulatory review and development. Other studies include, acute and chronic HIV infection cohorts.

 

Dr. Sawe is the Clinical Research Site (CRS) leader for the KEMRI/WRP, Kericho,  Clinical Research Center (CRC) for the US National Institute of Allergy and Infectious Disease (NIAID), Division of AIDS (DAIDS):

1)  AIDS Clinical Trials Group (ACTG),

2) International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT),

3)  HIV Vaccine Trials Network (HVTN) and

4) Corona Vaccine and Prevention Network (COVPN).

The studies conducted under these networks include, HIV “remission/cure” acute HIV infections in adults and neonates,   optimal treatment after single dose nevirapine exposure, public health approach to viral load monitoring in resource limited settings, Tuberculosis and HIV co-infections, cryptococal meningitis, Kaposi’s sarcoma and immune reconstitution syndrome, evaluation of  interventions to treat and prevent HIV infection and its consequences in infants, children, adolescents and pregnant/postpartum women through the conduct of high quality clinical trials.

Since 2004 Dr. Sawe has also been in charge of the KEMRI/WRP South Rift Valley Province (SRV) United Sates President’s Emergency Plan For AIDS Relief (PEPFAR) funded compressive HIV/AIDS prevention, care and treatment program that serves a population of 4 million people. The SRV PEPFAR program includes among others; HIV Care and Treatment, HIV Counseling and Testing (HCT), Prevention of Mother to Child transmission of HIV infection (PMTCT), Voluntary Medical Male Circumcision  (VMMC), HIV Prevention (those targeting most at risk populations) and orphans and vulnerable children.