Dr. Simiso Sokhela, a published researcher, started her medical career when HIV was the leading cause of death in Sub-Saharan Africa, due to lack of access to antiretrovirals. She worked within South Africa’s public and private health sectors with a personal vision of reversing the HIV tide. In 2013, she joined Ezintsha as senior research medical officer and led the establishment of HIV treatment research sites. Her operational and clinical governance expertise have ensured that clinical outcomes for HIV and more recently, COVID-19 clinical trial participants, have been unparalleled. Her focus on staff wellness and training ensures a highly motivated clinical workforce with a drive for quality healthcare. She is involved in training programs with the South African HIV Clinicians society and is currently completing her MSc (Med) Bioethics and Health Law with the University of Witwatersrand. She is currently Principal Investigators on several HIV and COVID treatment trials.